Vinales nampak belum nyetel dengan motor RS-GP milik Aprilia.
Pada lap ke-20, drama terjadi di barisan depan, Marc Marquez sempat menerobos posisi puncak dari Francesco Bagnaia.
Duel kedua pembalap terjadi hingga memasuki last lap, hingga akhirnya Bagnaia berhasil melewati garis finish lebih cepat dan menjuarai MotoGP Aragon 2021.
Baca Juga: MotoGP Aragon 2021 – Strategi Fabio Quartararo untuk Redam Keganasan Francesco Bagnaia
Berikut Hasil MotoGP Aragon 2021, Minggu (12/9/2021)
| POS. | PEMBALAP | NEGARA | TIM | WAKTU/SELISIH |
| 1 | Francesco Bagnaia | ITA | Ducati Team (GP21) | 41m 44.422s |
| 2 | Marc Marquez | SPA | Repsol Honda (RC213V) | +0.673s |
| 3 | Joan Mir | SPA | Suzuki Ecstar (GSX-RR) | +3.911s |
| 4 | Aleix Espargaro | SPA | Aprilia Gresini (RS-GP) | +9.269s |
| 5 | Jack Miller | AUS | Ducati Team (GP21) | +11.928s |
| 6 | Enea Bastianini | ITA | Avintia Ducati (GP19)* | +13.757s |
| 7 | Brad Binder | RSA | Red Bull KTM (RC16) | +14.064s |
| 8 | Fabio Quartararo | FRA | Monster Yamaha (YZR-M1) | +16.575s |
| 9 | Jorge Martin | SPA | Pramac Ducati (GP21)* | +16.615s |
| 10 | Takaaki Nakagami | JPN | LCR Honda (RC213V) | +16.904s |
| 11 | Iker Lecuona | SPA | KTM Tech3 (RC16) | +17.124s |
| 12 | Alex Rins | SPA | Suzuki Ecstar (GSX-RR) | +17.710s |
| 13 | Pol Espargaro | SPA | Repsol Honda (RC213V) | +19.680s |
| 14 | Miguel Oliveira | POR | Red Bull KTM (RC16) | +22.703s |
| 15 | Danilo Petrucci | ITA | KTM Tech3 (RC16) | +25.723s |
| 16 | Cal Crutchlow | GBR | Monster Yamaha (YZR-M1) | +26.413s |
| 17 | Johann Zarco | FRA | Pramac Ducati (GP21) | +26.620s |
| 18 | Maverick Viñales | SPA | Aprilia Gresini (RS-GP) | +27.128s |
| 19 | Valentino Rossi | ITA | Petronas Yamaha (YZR-M1) | +32.517s |
| 20 | Luca Marini | ITA | Sky VR46 Avintia Ducati (GP19)* | +39.073s |
| Jake Dixon | GBR | Petronas Yamaha (YZR-M1) | DNF | |
| Alex Marquez | SPA | LCR Honda (RC213V) | DNF |
*Pembalap rookie (debutan)
** DNF = Gagal finis