Berikut klasemen akhir MotoGP 2021
| Pos. | Pembalap | Motor | Negara | Poin |
|---|---|---|---|---|
| 1 | Yamaha | FRA | 278 | |
| 2 | Ducati | ITA | 252 | |
| 3 | Suzuki | SPA | 208 | |
| 4 | Ducati | AUS | 181 | |
| 5 | Ducati | FRA | 173 | |
| 6 | KTM | RSA | 151 | |
| 7 | Honda | SPA | 142 | |
| 8 | Aprilia | SPA | 120 | |
| 9 | Ducati | SPA | 111 | |
| 10 | Aprilia | SPA | 106 | |
| 11 | Ducati | ITA | 102 | |
| 12 | Honda | SPA | 100 | |
| 13 | Suzuki | SPA | 99 | |
| 14 | KTM | POR | 94 | |
| 15 | Honda | JPN | 76 | |
| 16 | Honda | SPA | 70 | |
| 17 | Yamaha | ITA | 47 | |
| 18 | Yamaha | ITA | 44 | |
| 19 | Ducati | ITA | 41 | |
| 20 | KTM | SPA | 39 | |
| 21 | KTM | ITA | 37 | |
| 22 | Honda | GER | 14 | |
| 23 | Ducati | ITA | 12 | |
| 24 | Yamaha | ITA | 12 | |
| 25 | KTM | SPA | 6 | |
| 26 | Aprilia | ITA | 4 | |
| 27 | Ducati | SPA | 1 | |
| 28 | Yamaha | GBR | ||
| 29 | Yamaha | USA | ||
| 30 | Yamaha | GBR |